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The Route


Opening hours 

Thursday 30.7.2015

8:00-9:00 (parallel activities: coffee)

12:30-14:00 (parallel activities: lunch)

18:00-19:00 (parallel activities: posters and ice cream)


Friday 31.7.2015

8:00-9:00 (parallel activities: coffee)

13:00-14:00 (parallel activities: lunch)


The Route is an interactive sequence of displays where participants can go through the biobanking processes step by step. This year (2015), the route will focus on using clinical samples in a research context, where we plan to offer HOBB participants a chance to follow the route of clinical tissue samples to be used in a research project context. The research project will also require associated blood samples. The research projects will require that molecules be extracted from the samples to be used in genetic and genomic sequencing and that the sample related data and research data be associated with clinical associated data for clinical validation and potential dissemination of results.

The Route in practice.  At the start of the Route, in the first step Ethics & Regulation, biobankers with the research project requirements in hand will be able to evaluate how the process of recruiting patients', in particular the content of the informed consent, affects the use of the samples they collect. Different scenarios of how consent is collected as part of health care will be addressed. It will also show how the permission granted by the patient and EU regulations condition the dissemination of research results.

Based on the project requirements, during the next step, Biobanking practice & Pre-analytics, tissue sample preparation will be carried out, based on the project requirements. Tissue sample processing, following the sample from the operating theatre to its final biobank storage of either cryopreservation, fresh frozen or pathology archive will be explored through the pathology tissue grossing room and then directed to company providers. Here the various tissue processing technologies will be demonstrated from fresh tissue transportation to formalin fixed paraffin embedding facilities and the transformation of FFPE blocks in Tissue Micro Arrays using precision automated systems and technologies for extracting nucleic acids from different processed tissue. This step will also explore the use of informatics systems to collect data, annotate samples during their acquisition and use with data, quality control information and images.

The Sample analysis step will demonstrate how the samples are prepared from nucleic acids and analyzed using genomics, transcriptomics, proteomics and metabolomics technologies. In the Data analysis step the results of the different omics datasets are combined with the available sample associated clinical and pathological data to demonstrate how the biobank collected data increase the value of the sample. This will provide input for clinically applicable tissue diagnostics.

The final Dissemination step will focus on publication of results and other methods of distribution  for the information such as the BBMRI-ERIC networking projects such as (BBMRI-ERIC) and others to present their work.

The HandsOn conference gives participants the opportunity to discuss their views with experts from industry, academy and authorities that regulate research. Participants are more than welcome to share their ideas in Meet the Expert sessions and Legal and Scientific Café as well as in the other sessions in the conference.


The steps of the Route

The research process:

  • Ethics & Regulation: ethics and law as regulations and pre-requisites for use of biobank samples in  research.
  • Biobanking practice & Pre-analytics: the journey of fresh tissue from the donor patient to the biobank using technologies to ensure that the tissue is suitable for the conservation method and nucleic acid extraction from various tissue types for sample analysis.
  • Sample Analysis: genomics, proteomics, metabolomics and transcriptomics instruments.
  • Data Analysis: statistical analysis of omics data and association of  clinical pathological data for validation
  • Dissemination: publication and distribution of results.



  • Inform and educate participants about biobanking from the biobanker, researcher and industry point of view
  • Gain  hands-on experience of the biobanking process , this year highlighting tissue samples
  • Gather information on how to improve the biobanking process
  • Open a dialogue with all communities involved in biobanking
  • Set the agenda for future research



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